Findings

Lymphocytic infiltrates are noted at the epidermaldermal junction and within the dermis. Hyperkeratosis and follicular plugging are present.

Impression

Lupus erythematosus

Pathology Pointer

Histopathologic changes of lupus erythematosus include follicular plugging, hydropic degeneration of the basal layer, thickening and irregularity of the basement membrane, dermal edema, and lymphocytic infiltrates within the dermis and subcutaneous tissue.

Preparation

Fixed, H & E stain

View

Light micrograph

Specimen

Skin

Image Credit

Katsumi M. Miyai, M.D., Ph.D
Department of Pathology
School of Medicine
University of California, San Diego