Findings

In this high-power view of the growth (epiphyseal) plate, the zones of proliferation, hypertrophy and calcification can be seen from top to bottom. The result of this process is the formation of calcified cartilage trabeculae, which are later remodeled by osteoblasts to bone trabeculae.

Comment

Trabeculae at the bottom of the image are most likely bone trabeculae (note osteocytes in lacunae).

Preparation

Paraffin section, hematoxylin and eosin

View

High-power light microscopy

Specimen

Developing endochondral bone

Image Credit

V. Eroschenko, Ph.D.
Department of Biological Sciences
WAMI Medical Program
University of Idaho