Findings

- Left panel shows a part of tophi made up of urate cry stals with sheaf -like appearance and peripheral granulomatous reaction with giant cells. - Right panel shows that urate cry stals are intensely biref ringent under polarized light.

Impression

Gouty arthritis, tophi. Microscopic v iew

Preparation

Fixed, H & E stain

View

Light micrograph

Specimen

Soft tissue adjacent to a joint

Image Credit

Parviz Haghighi, M.D.
Department of Pathology
School of Medicine
University of California, San Diego