Findings

In this high-power view of a portion of the margin of a corpus luteum, the granulosa lutein cells and theca lutein cells are clearly seen. Note also the presence of a primordial follicle and a unilaminar primary follicle adjacent to the corpus luteum in the surrounding ovarian stroma.

Comment

Under the influence of luteinizing hormone (LH) from the anterior pituitary gland, both the granulosa cells and theca interna cells enlarge and transform into secretory granulosa lutein and theca lutein cells, respectively. These cells then begin to secrete estrogen and large amounts of progesterone.

Preparation

Paraffin section, hematoxylin and eosin

View

High-power light microscopy

Specimen

Ovary

Image Credit

V. Eroschenko, Ph.D.
Department of Biological Sciences
WAMI Medical Program
University of Idaho