In this image, an atretic multilaminar primary follicle is shown. Note the degenerating
granulosa cells and the collapsed remnant of the
zona pellucida. In the surrounding ovarian
stroma are several other primary follicles.
Comment
The glycoproteinaceous zona pellucida is more
resistant to degradation than the primary oocyte
and granulosa cells, and thus remains as a marker of atretic follicles.
Preparation
Paraffin section, hematoxylin and eosin
Specimen
Ovary
Image Credit
V. Eroschenko, Ph.D.
Department of Biological Sciences
WAMI Medical Program
University of Idaho
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