Findings

In this high-power image, the interface between the granulosa cells of a multilaminar primary follicle and the immediate surrounding ovarian stroma is clearly seen. Here, the ovarian stroma differentiates into two layers, the theca interna and theca externa. Note the numerous capillaries in the theca interna.

Comment

The theca interna produces an androgen, androstendione, that is converted by granulosa cells into the estrogen, estradiol.

Preparation

Paraffin section, hematoxylin and eosin

View

High-power light microscopy

Specimen

Ovary

Image Credit

V. Eroschenko, Ph.D.
Department of Biological Sciences
WAMI Medical Program
University of Idaho