Findings

In this medium-power image, the mucosa of the appendix is evident. The intestinal glands contain numerous goblet cells. The lamina propria is characterized by numerous and closely spaced large lymphoid nodules with germinal centers, some of which may extend into the submucosa. The muscularis externa can be seen in the left portion of the image.

Comment

The mucosa of the appendix is similar to that of the colon in that it lacks villi and has numerous goblet cells. However, the intestinal glands of the appendix are shallower and less abundant than those of the colon.

Preparation

Paraffin section, hematoxylin and eosin

View

Medium-power light microscopy

Specimen

Appendix

Image Credit

Katsumi M. Miyai, M.D., Ph.D
Department of Pathology
School of Medicine
University of California, San Diego