Findings

In the gastroduodenal junction, there is an abrupt transition in mucosal morphology. The smooth surface of the gastric pylorus is distinct from that of the duodenum which contains numerous finger-like projections called villi. Note the pyloric sphincter and the mucus-producing Brunner's glands in the submucosa of the duodenum.

Comment

The Brunner's glands secrete alkaline mucus that neutralizes the acidic chyme coming from the stomach.

Preparation

Paraffin section, hematoxylin and eosin

View

Low-power light microscopy

Specimen

Gastroduodenal junction

Image Credit

Katsumi M. Miyai, M.D., Ph.D
Department of Pathology
School of Medicine
University of California, San Diego