In this higher magnification of the previous image, the
gastric pits and glands of the fundic stomach are shown
in greater detail. Light-staining surface mucous cells comprise the luminal epithelium and continue into the
gastric pits. Beneath the gastric pits, the apical regions of the gastric glands contain large eosinophilic parietal (oxyntic) cells. The basal region of the gastric glands contains the basophilic chief (zymogenic) cells.
A lamina propria surrounds the gastric glands.
Comment
Parietal cells secrete hydrochloric acid and intrinsic factor. Chief cells secrete pepsinogen which is converted to the proteolytic enzyme, pepsin, in an acidic environment. The secretion of the surface mucous cells
protects the mucosa from the secretions of the gastric
glands.
Preparation
Paraffin section, hematoxylin and eosin
View
High-power light microscopy
Specimen
Fundic,
Stomach
Image Credit
V. Eroschenko, Ph.D.
Department of Biological Sciences
WAMI Medical Program
University of Idaho
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