Comment

Fasciculations: Non-volitional twitching of muscle fibers. This can occur with a number of disorders, including ALS where lower motor neuron degeneration results in denervation of the muscle. The fasciculations occur spontaneously and are visible upon gross inspection. This can affect any muscle group, including arms, legs, tongue. ALS is accompanied by other findings and symptoms, in particular progressive motor weakness. Other disorders associated with fasciculations include: post exercise, benign fasciculation syndrome (eye lids, limbs), meds, stimulants (e.g. caffeine), and assorted metabolic processes (e.g. hyperthyroidism).

Image Credit

Charlie Goldberg, M.D.